We investigated prospectively the incidence and determinants of work-related specific skin
sensitization in a cohort of 769 apprentices, including 417 in animal health technology, 230
in pastry-making, and 122 in dental-hygiene technology. Subjects were recruited when
starting exposure to laboratory animals, flour, or latex. A questionnaire and skin-prick tests
with common and work-related allergens were administered on entry and at follow-up visits
from 8 to 44 mo; information on number of hours of exposure to specific allergens was …